ABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor. Targets&IC50: Adenosine kinase :ic50 1.7nM, Animal Research: Rats are fasted for 16 hours prior to use. At the beginning of the experiment, each rat is weighed, and then

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Vulcanchem offers qualified products for CAS No. 1188890-28-9(ABT 702 Dihydrochloride), please inquire us for more detail. ABT-702 dihydrochloride: CAS Number: 1188890-28-9: 1.2 Relevant identified uses of the substance or mixture and uses advised against; Identified uses: For research use only, not for human or veterinary use. 1.3 Details of the supplier of the safety data sheet; Company: Abmole Bioscience Inc. 8300 FM 1960 West, Suite 450 Houston, TX 77070, USA These studies demonstrated that ABT-702 suppressed collagenase and stromelysin gene expression in treated animals. In addition, the activator protein-1 and nuclear factor-κB binding activity was also decreased.

ABT-702 is a novel, potent non-nucleoside Adenosine kinase inhibitor with an IC50 of 1.7 nM. It has oral activity in animal models of pain and inflammation. Purity & Quality Control Choose Selective Adenosine Kinase Inhibitors A2721 Sigma-Aldrich ABT-702 dihydrochloride Synonym: 4-Amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido [2,3-d]pyrimidine CAS Number 214697-26-4 (free base) Data Sheet SDS Handling Instructions ABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor (IC50 =1.7 nM). For research use only. We do not sell to patients. ABT 702 is a novel, potent nonnucleoside AK inhibitor.

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ABT 702 hydrochloride. catalog : 2372/10. quantity : 10 mg. price : 297 USD. more info or order : Tocris Bioscience product webpage. citations: 2. Reference; Hobson B, Merritt K, Bachtell R. Stimulation of adenosine receptors in the nucleus accumbens reverses the expression of cocaine sensitization and cross-sensitization to dopamine D2

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The involvement of adenosine signaling in the anti-inflammation effect of ABT-702 was supported by the TNF-α release blocking effect of A2AAR antagonist in AGA-treated microglial cells. SIGNIFICANCE: These results suggest a role for AK in regulating adenosine receptor signaling in the retina.

214697-26-4 ABT-702 treated obese ZSF1 rats exhibited reduced expression of myocardial carbonic anhydrase 9 and collagen, surrogate markers of myocardial hypoxia. Conclusions: Upregulation of vascular ADK mitigates adenosine-facilitated conducted vasodilation in obese ZSF1 rats and in patients with HFpEF.

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Benämning enligt SS-EN 13108-1: ACslit Provtagning ska utföras på massa från bil vid asfaltverk enligt TRVMB 702. stämmelser för tjänstemän hos Stockholms kommun, ABT 75. Med "statliga Idrottsförbund (SKIF) var vid årets slut 22 med sammanlagt 5 702 betalande med-.
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ABT-702 is a novel, potent non-nucleoside Adenosine kinase inhibitor with an IC50 of 1.7 nM. It has oral activity in animal models of pain and inflammation. Purity & Quality Control Choose Selective Adenosine Kinase Inhibitors

Cited in 2 publications. 27 Sep 2019 Intracellular adenosine levels were increased by incubating cells for 72h with ABT 702 dihydrochloride (ABT, 15µM), an adenosine kinase 19 Feb 2020 To assess the role of AK we used ABT-702, an AK inhibitor.

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ABT -06 vid totalentreprenad, har en bor- rentreprenör tio års Åberopa AB-04 eller ABT-06 så att båda parter vet vad 031-702 56 00 mobil 070-723 56 00.

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214697-26-4 - RQCXKDWOCUJWQZ-UHFFFAOYSA-N - ABT 702 - Similar structures search, synonyms, formulas, resource links, and other chemical information.

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